human immune system

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слайд 1 human immune system cells cooperation in immune response primary or central lymphoid organs are responsible for synthesis and maturation of immunocompetant cells. these include the bone marrow and the thymus. peripheral or secondary lymphoid organs are sites where the lymphocytes localise, recognise foreign antigen and mount response against it. these include the lymph nodes, spleen, tonsils, adenoids, appendix, and clumps of lymphoid tissue in the small intestine known as peyer's patches. they trap and concentrate foreign substances, and they are the main sites of production of antibodies. white blood cells phagocytes - neutrophils macrophages lymphocytes cells of the immune system white blood cells * lymphocyte (could be b cell or t cell!) * lymphocytes present in lymphoid organs and in blood groups t-lymphocytes (grow up in thymus) b-lymphocytes (grow up in bone marrow) each one has receptors for a specific antigen recognize millions of different antigens! diversity generated …
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eat bugs decreased in patients with aids cytotoxic t cells cd8+ (and cd4-) kill virus-infected cells and tumor cells t lymphocytes * cd8+ t cells surrounding tumor cell * lymphocytes belong to innate immunity arm no highly variable receptors like t and b cells main job: recognize and kill damaged or infected cells antigens don’t have to be bound to mhcs or displayed by other cells! natural killer cells * natural killer cell * natural killer cell (top) killing infected cell (bottom) * antigen-presenting cells main job: catch antigens and display them to lymphocytes dendritic cells have fine cytoplasmic projections present all over body: skin, lymph nodes, organs capture bug antigens, display to b and t cells other apcs macrophages eat bugs and present antigens to t cells, which tell macrophages to kill bugs b cells present antigens to helper t cells, which tell b cells to make antibodies * …
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слайд 1 human immune system cells cooperation in immune response primary or central lymphoid organs are responsible for synthesis and maturation of immunocompetant cells. these include the bone marrow and the thymus. peripheral or secondary lymphoid organs are sites where the lymphocytes localise, recognise foreign antigen and mount response against it. these include the lymph nodes, spleen, tonsils, adenoids, appendix, and clumps of lymphoid tissue in the small intestine known as peyer's patches. they trap and concentrate foreign substances, and they are the main sites of production of antibodies. white blood cells phagocytes - neutrophils macrophages lymphocytes cells of the immune system white blood cells * lymphocyte (could be b cell or t cell!) * lymphocytes present in lymphoid organs...

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