the immune system: humoral and cell-mediated immunity

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powerpoint presentation the immune system: humoral and cell-mediated immunity a complex system of organs, tissues, cells, and processes that protect us from disease. enables the body to recognise anything that is different from itself (i.e. “foreign”) and that is potentially harmful. creates defences against these invaders, which are called pathogens. divided into two broad categories: ‘innate immunity’ and ‘acquired immunity.’ the immune system iavi vaccine literacy library | module 3 2 iavi vaccine literacy library | module 3 innate immune defences first to respond to any pathogen. not specific to one pathogen. cannot usually be “taught” to respond better by a vaccine. often not enough to get rid of pathogens as the first line of defence and a second line of defence kicks in. immunity and immune responses acquired immunity second line of defence of the body. activated only after our immune system has “seen” and “recognised” a pathogen. directed …

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found at the surface of the t and b cells of the immune system, and they can recognise antigens or part of the antigens presented by the antigen-presenting cells (apcs). there is a vast diversity of b- and t- cell receptors allowing the human immune system to recognise a very large number of pathogens. humoral immune response iavi vaccine literacy library | module 3 binding antibody produced in large quantities following infection. recognises and binds to parts of a foreign body but cannot directly prevent infections or destroy the pathogen. requires the involvement of other immune mechanisms to destroy the foreign agent. neutralising antibody recognises and binds to a pathogen. can neutralise pathogens by blocking the pathogen from entering its host cell. neutralisation can result in loss of infectivity. broadly neutralising antibody (bnab) can recognise a wide range of viruses even if they are different from the virus that initially …

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powerpoint presentation the immune system: humoral and cell-mediated immunity a complex system of organs, tissues, cells, and processes that protect us from disease. enables the body to recognise anything that is different from itself (i.e. “foreign”) and that is potentially harmful. creates defences against these invaders, which are called pathogens. divided into two broad categories: ‘innate immunity’ and ‘acquired immunity.’ the immune system iavi vaccine literacy library | module 3 2 iavi vaccine literacy library | module 3 innate immune defences first to respond to any pathogen. not specific to one pathogen. cannot usually be “taught” to respond better by a vaccine. often not enough to get rid of pathogens as the first line of defence and a second line …

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