dori vositalari haqida ma'lumotlar

PDF 62 pages 418.5 KB Free download

62 pages

FaylHub.uz

Download via Telegram

Size 418.5 KB

File type PDF

Pages 62

Updated Dec 2025

Page preview (5 pages)

Scroll down 👇

1 / 62

dori vositalarining xomilaga kursatadigan asosiy nojuya ta'sirlari homiladorlik va emizikli ayollarda dori vositalarini qo'llash. dori vositalarining yoshga bog'liq jixatlari. features of using of drugs during pregnancy and lactation. age aspects of clinical pharmacology. katta o'qituvchi t.f.n. pudatova d.b. dori vositalarining homilaga ko'rsatadigan asosiy nojo'ya ta'sirlari adverse drug reactions on the fetus  embriotoksik ta'sir  teratogen ta'sir  homiladorlik davrida 60-80% aѐllar turli sabablarga ko'ra dori vositalarini qabul qiladilar  chaqaloqlarda uchraydigan tug'ma anomaliyalarning 5% dan ortig'i homiladorlik davrida onaning dori vositalarini qabul qilganligi bilan bog'liq  fetotoxic effects  teratogenic effects  60-80% of women during pregnancy take drugs for various reasons  over 5% of congenital anomalies of the newborn associated with drugs the mother during pregnancy homila rivojlanishida dori vositalarining embriotoksik ta'siri ko'prok namoѐn bo'lishi mumkin bo'lgan kritik davrlar critical periods in fetal development  i – kritik davr – amnionning implantatsiya davri. homiladorlikning birinchi haftasi. dv …

2 / 62

ent. 18-40 weeks of pregnancy. action drugs is particularly dangerous in the 18-22 weeks of gestation and manifest with anomalies of the central nervous system, hematopoietic system and endocrine systems. fetotoxic, teratogenic effects not observed. dori vositalarining teratogen ta'siri bo'yicha klassifikatsiyasi the classification of drugs according to the degree of teratogenicity  a kategoriya – homila uchun mutlako havfsiz. teratogen ta'siri tajribada ham, klinikada ham aniqlanmagan  b kategoriya – tajribada teratogen ta'siri bo'lmagan, lekin klinik tekshiruvlar haqida ma'lumotlar yo'q  s kategoriya – homila uchun havfli ta'sir ehtimoli bor, lekin homilador uchun ko'rsatadigan terapevtik ta'siri ko'llashni oqlaydi  d kategoriya – homila uchun havfli ta'siri aniq, lekin haѐtiy ko'rsatma tufayli ularni qo'llash shart  x kategoriya – teratogen ta'siri eksperimentda ham klinikada ham isbotlangan. homiladorlik davrida ularni qo'llash taqiqlanadi  category a - completely safe for the fetus. teratogenicity of drug was not observed in the experiment no clinical …

3 / 62

pregnancy  the penetration of drugs through the placental barrier  features of change the pharmacokinetics of drugs in organism of the fetus homilador aѐllarda dori vositalari farmakokinetikasining o'ziga xos xususiyatlari features of pharmacokinetics of drugs during pregnancy  dori vositalarining so'rilishi ko'payadi, sababi – oshqozon-ichak trakti motorikasining susayishi  dori vositalarining qondagi oqsillar bilan bog'lanishi susayadi, sababi – qonda oqsil miqdorining kamayishi  dori vositalarining jigarda metabolizmi susayadi, sababi – fermentlar aktivligining kamayishi va jigarda qon oqish tezligining susayishi  dori vositalarining eliminatsiyasi susayadi, sababi – buyrakda koptokchalar filtratsiyasining susayishi va kanalchalarda reabsorbtsiyaning kuchayishi  the absorption of drugs enhances due to the slow motility of the gastrointestinal tract  reduces the degree of drug binding to plasma proteins, by reducing the number of plasma proteins  the metabolism of drugs in the liver slows down , due to the slowing of blood flow in the liver and reduce …

4 / 62

bo'ladi. glyukuronlovchi fermentlar faolligi sust, sulfatlovchi fermentlar faolligi yuqori bo'ladi  dvlarining qondagi oqsillar bilan bog'lanishi cusayadi  dvlarining homila organizmidan chiqarilishida yo'ldosh birinchi o'rinni, buyrak ikkinchi o'rinni egallaydi homiladorlik davrida antibiotiklarning qullanilishi dv guruxlari homiladorlik trimestrlari 1-3 oylik 3-8 oylik oxirgi haftalar penitsilinlar + + + tsefalosporinlar + + + karbopenemlar + + + makrolidlar + + + linkomitsin + + + fuzidin + + + vankomitsin +e ; -p +e ; -p +e ; -p nefrotoksik, ototoksik polimiksinlar +e ; -p +e ; -p +e ; -p nefrotoksik aminoglikozidlar - - - oto-, nefrotoksik tetratsiklinlar - - - suyak to'qimasi o'sishi, tish emali buzilishi levomitsetin - - - aplastik anemiya rifampitsin - - - teratogen ta'sir antibakterial dori vositalarining homiladorlik davrida qo'llanilishi preparatlar homiladorlik trimestrlari 1-3 oylik 3-8 oylik oxirgi haftalar ftorxinolonlar - - - bo'g'imlar tog'ay to'qimasining o'sishini to'xtatadi sulfanilamidlar + + - chaqaloqlarda giperbilirubinemiya, gemolitik anemiya …

5 / 62

i dv guruxlari homiladorlikda qo'llanilishi markaziy alfa-agonistlar + ganglioblokatorlar + simpatolitiklar - rinoreya , bronxoreya beta-adrenoblokatorlar - bachadon-platsenta qon aylanishining buzilishi, bradikardiya, nafas olishning sekinlashuvi kaltsiy antagonistlari + venoz vazodilyatatorlar – nitratlar + arterial vazodilyatatorlar – apressin + aralash vazodilyatatorlar – natriy nitroprussid + apf ingibitorlari - teratogen ta'sir angiotenzin ii-antagonistlari - teratogen ta'sir diuretik dv larining homiladorlikda qo'llanilishi dv guruxlari homiladorlikda qo'llanilishi karbongidraza ingibitorlari - oѐq qo'llar rivojlanishi anomaliyalari aldosteronning bevosita va bilvosita antagonistlari - teratogen ta'sir tiazidli diuretiklar - giponatriemiya, trombotsitopeniya, chaqaloqlar sariqligi xalqa diuretiklari -uregit -furasemid - chaqaloqlarda karlik, gipoglikemiya, homila o'limi + vitaminlarning homiladorlik davrida ahamiyati vitaminlar homiladorlikdagi anomaliyalar gipovitaminoz a ko'z, siydik ayiruv-jinsiy a'zolar anomaliyalari gipervitaminoz a tanglayning ajralishi, anentsefaliya gipovitaminoz v rivojlanish anomaliyalari – tanglayning ajralishi, yurak nuqsonlari, gidronefroz, gidrotsefaliya gipovitaminoz s homila barvaqt tushishi gipervitaminoz s gipervitaminoz e miya, ko'z va skelet anomaliyalari antikoagulyantlarning homiladorlik davrida qo'llanilishi dv guruhi homiladagi o'zgarishlar bevosita antikoagulyantlar …

Want to read more?

Download all 62 pages for free via Telegram.

Download full file

About "dori vositalari haqida ma'lumotlar"

dori vositalarining xomilaga kursatadigan asosiy nojuya ta'sirlari homiladorlik va emizikli ayollarda dori vositalarini qo'llash. dori vositalarining yoshga bog'liq jixatlari. features of using of drugs during pregnancy and lactation. age aspects of clinical pharmacology. katta o'qituvchi t.f.n. pudatova d.b. dori vositalarining homilaga ko'rsatadigan asosiy nojo'ya ta'sirlari adverse drug reactions on the fetus  embriotoksik ta'sir  teratogen ta'sir  homiladorlik davrida 60-80% aѐllar turli sabablarga ko'ra dori vositalarini qabul qiladilar  chaqaloqlarda uchraydigan tug'ma anomaliyalarning 5% dan ortig'i homiladorlik davrida onaning dori vositalarini qabul qilganligi bilan bog'liq  fetotoxic effects  teratogenic effects  60-80% of women during pregnancy take drugs for various reas...

This file contains 62 pages in PDF format (418.5 KB). To download "dori vositalari haqida ma'lumotlar", click the Telegram button on the left.

Tags: dori vositalari haqida ma'lumot… PDF 62 pages Free download Telegram