klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii

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naibolee chastiy simptom bronxolegochnix zabolevaniy natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii klinicheskaya farmakologiya lekarstvennix sredstv, vliyayushix na bronxialnuyu proxodimost klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * bronxodilyatatori stimulyatori adrenoretseptorov m-xolinoblokatori ingibitori fosfodiesterazi (metilksantini) protivovospalitelnie antiastmaticheskie preparati: glyukokortikoidi stabilizatori membran tuchnix kretok blokatori leykotrienovix retseptorov mukolitiki, otxarkivayushie i protivokashlevie ls lekarstvennie sredstva, vliyayushie na bronxialnuyu proxodimost natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii bronxodilyatatori maksimalnaya plotnost m-xolinoretseptorov adrenoretseptorov opredelyaetsya na urovne krupnix i srednix bronxov maksimalnaya plotnost  2-adrenoretseptorov opredelyaetsya na urovne srednix i melkix bronxov plotnost -adrenoretseptorov v bronxialnom dereve znachitelno previshaet plotnost -retseptorov klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya …

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podavlenie sekretsii mediatorov tuchnimi kletkami stimulyatsiya m-xolinoretseptorov: bronxospazm povishenie produktsii sekreta v bronxax povishenie osvobojdeniya mediatorov tuchnimi kletkami povishenie dvigatelnoy aktivnosti resnichek mertsatelnogo epiteliya bronxov klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii bronxodilyatatori simpatomimetiki adrenalin efedrin beta-adrenomimetiki m-xolinolitiki ksantini antagonisti leykotrienovix retseptorov klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii adrenalin adrenalin (epinefrin) - vozbujdaet vse vidi adrenoretseptorov chuvstvitelnost beta-adrenoretseptorov znachitelno vishe, chem alfa-adrenoretseptorov pri vrojdennoy ili priobretennoy refrakternosti 2 -adrenoretseptorov obichnie dozi adrenalina ne ustranyayut bronxospazm klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii adrenalin farmakodinamika dilyatatsiya gladkoy muskulaturi bronxov usilenie mukotsiliarnogo klirensa povishenie …

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ivnostyu klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii adrenalin nejelatelnie effekti: taxikardiya, narushenie krovosnabjeniya miokarda pod'em ad narushenie mikrotsirkulyatsii v tkanyax i organax giperglikemiya tremor zaderjka mochi pokazaniya k primeneniyu: tyajeliy pristup bronxospazma, ne kupiruyushiysya drugimi beta-stimulyatorami ili efedrinom. klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii efedrin efedrin - nepryamoy simpatomimetik : sposobstvuet osvobojdeniyu noradrenalina tormozit obratniy zaxvat noradrenalina povishaet chuvstvitelnost vsex vidov retseptorov k noradrenalinu i adrenalinu farmakodinamika po sravneniyu s adrenalinom bolee slaboe, no prodoljitelnoe deystvie virajenniy stimuliruyushiy effekt na tsns klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii efedrin farmakokinetika vvoditsya …

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y opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii efedrin nejelatelnie effekti: stimuliruyushee vliyanie na tsns - vozbujdenie, bespokoystvo, bessonitsa, trevoga, strax u detey do 5 let - patologicheskoe ugnetenie tsns vozmojno razvitie psixicheskoy i fizicheskoy zavisimosti pokazaniya k primeneniyu: kupirovanie i profilaktika tyajelix pristupov bronxospazma klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii efedrin uvelichenie prodoljitelnosti bronxodilyatatsii snijenie bronxoliticheskogo deystviya umenshenie pressornogo effekta farmakodinamichekiy antagonizm vzaimodeystvie: adrenalin -adrenoblokatori -adrenoblokatori sredstva, ugnetayushie tsns klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii beta-adrenomimetiki preparati: izoproterenol (izadrin) ortsiprenalin (astmopent) salbutamol (ventolin) fenoterol (berotek) terbutalin (ayronil) formoterol (oksis turbuxayler) salmeterol (serevent, salmeter) klenbuterol klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra …

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ol 20,0 0,05 400 salbutamol 0,55 0,0004 1375 salmeterol 8,5 0,0001 85000 klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii beta-adrenomimetiki - vvodyatsya parenteralno, peroralno, ingalyatsionno - optimalniy put vvedeniya – ingalyatsionniy - biousvoyaemost iz jkt - 70-40% - biousvoyaemost so slizistoy bronxov bolee 10% - metaboliti obladayut beta-stimuliruyushey ili beta-blokiruyushey aktivnostyu farmakokinetika klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii beta-adrenomimetiki pokazaniya i osobennosti primeneniya pri umerennom bronxospazme - ingalyatsionno kupirovanie bronxospazma pri virajennom bronxospazme - parenteralno; effekt cherez 20-30 min (rasshiryayutsya melkie bronxi) klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii beta-adrenomimetiki pokazaniya i …

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naibolee chastiy simptom bronxolegochnix zabolevaniy natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii klinicheskaya farmakologiya lekarstvennix sredstv, vliyayushix na bronxialnuyu proxodimost klinicheskaya farmakologiya preparatov, primenyayushixsya pri sindrome bronxialnoy obstruktsii natsionalniy farmatsevticheskiy universitet kafedra klinicheskoy farmakologii s farmatsevticheskoy opekoy * bronxodilyatatori stimulyatori adrenoretseptorov m-xolinoblokatori ingibitori fosfodiesterazi (metilksantini) protivovospalitelnie antiastmaticheskie preparati: glyukokortikoidi stabilizatori membran tuchnix kretok blokatori leykotrienovix retseptoro...

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