nitrates (nitroglitserin, isosorbide dinitrate, isosorbide mononitrate, molsidomin)

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handouts: 1. drugs sent worldwide the beginning of the influence of hours vremya nastupleniya the maximum time for the start of the effect the duration of the effects of an hour 1 2 3 4 nitroglitserin under the tongue 2-3 2-5 min. 0.2-0.5 transbukkal 2-3 30-60 min. 3-5 to drink 30-40 1-2 s 4-5 maz 15-60 1-2 s 3-8 plastyr 60-120 2-10 s 24hours isosorbide dinitrate under the tongue spray 1-2 2-5 min 1 sublingvo 2.5-10 20-40 min 1-2 to drink 10-60 1-3 s 2-6 isosorbide mononitrate to drink 20-50 2-3 s 10-12 deposits tablets 20-50 2-3 s 20-24 molsidomin to drink 20 30-60 min 4-6 2. determining the effectiveness of nitrate indicators: · angina attacks, islam weight reduction and development accounted for intermediate t. · heart q is q, the number of branches of the increase in the volume of up to 7-10 q is q. · the decrease …

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e systolic pressure> 90mm.sim.ust.) · hypotension in patients 4. exertion stenocardia antianginal drugs concomitant diseases / conditions when the differential application. diseases nitrates beta-blockers calcium antagonists tachycardia be used with caution in choice of drugs only verapamil and diltiazem bradycardia choice of drugs not recommended only digidropiridinlar av blockades ii-iii degree recommended not recommended only digidropiridinlar atrium arrhythmia recommended often effective verapamil and diltiazem fibrillation arrhythmias only heavy stenocardia choice of drugs verapamil and diltiazem ventricles tachycardia recommended choice of drugs verapamilni use with caution bronxoobstruktiv syndrome recommended you can use small doses cardioselektiv recommended pregnancy with care recommended not recommended arterial hypertension recommended choice of drugs choice of drugs after heart attack recommended choice of drugs recommended heart failure only heavy stenocardia choice of drugs individual approach hyperlipidemia choice of drugs cardioselektiv choice of drugs 5. myocardial infarction (acute phase), the application of patients with thrombolytic agents. drug vehicles …

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in) pindolol and other private simpatomimetik activity dvla, peaceful case, the hosts diminish. i degree av block pindolol and labetololni attendance checking, however, the pp should not exceed 0.26 sec. chronic heart failure vazodilyatatsiya featuring b-ablni (karvedilol nebivalol), and metoprololni goals. spontaneous (vazospastik) angina you can go all the b-ablni not. if necessary kardioselektiv or vazodilyatatsiya properties dvla can go. intermittent claudication can not be prescribed. if necessary, cautiously kardioselektiv or vazodilyatatsiya feature dvla is prescribed. q overactive thyroid or diabetes biological b-1-selective ablni can go. mental depression lipid-soluble b-ablni (propranolol, metoprolol, oksprenolol and b.) can not be prescribed. water-soluble dvla (atenolol, nadolol, sotalol, and b.). tireotoksikoz often applied to non-b-abl. private simpatomimetik activity is not in accordance with the dvla to use. feoxromotsitoma competitive dv - labetolol. after the rest of the p-abl phentolamine can be given. chronic renal failure lipophilic or mixed b-enforce the ablni. however, propranolol and …

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atherosclerosis 0 - + ++ cerebrospinal leak - (?) 0 (?) 0 ++ bronchitis, chronic obstructive pulmonary disease 0 - + ++ hyperlipidemia 0 - ++ ++ diabetes 0 - + + (?) glaucoma - + 0 0 me'da- esophageal reflux 0 ++ - 0 (?) q abza 0 ++ - 0 (?) diarrhea 0 - ++ 0 note: ++ - dv competition; + - positive dv; - a negative impact on dv; 0 -ta'sirning; ? - information not exactly. 8. antianginal dv and dv interaction with other groups. antianginal dv other drug the result of the interaction iza h nitrates calcium antagonist, hypotensive dvla, three siclic antidepressants, novokainamid xinidin nitroglitserinning hypotensive effect of increases. the effect of prolonged nitrates b-adrenoblokatorlar each dv antianginal effects of increased and decreased side effects. nitroglitserin acetylsalicylic acid q increases the amount of current nitroglitserin and its impact. heparin the effect of intravenous heparin …

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herapeutic activity increases. theophylline decreased hepatic clearance. muscle relaxants neyromushak blockade increases. anesthetic arterial hypotension indometacin hypotensive effect decreases kordaron digoxin digoksinni 2-fold increases in the amount of blood. digoxin eliminatsiyasi slow. digoxin dose is reduced by 2 times. warfarin increases the anticoagulant effect. warfarin slows down the metabolic clearance. verapamil digoxin digitoksin yugning blood volume increases. calcium antagonist b-abl calcium antagonist effect increases. a qb is reduced.av-conduction slowing down;bradycardia develops. calcium ant agonists, including nifedipine reduced hepatic clearance. phenobarbital slows the effects of calcium antagonists. increases the metabolic rate. cimetidine calcium ant agonists increase the amount of blood, their influence increases. calcium agonists antmetabolism slows down. smoking (nicotine) reduce the impact of calcium ant agonists. 9. antiplatelet drugs affecting the media the drug the dose acetylsalicylic acid, including: - intestinal fast-soluble shell covered with - ask + magnesium hydroxide aspirin, acetylsalicylic acid aspirin cardio, trombone ass kardiomagnil · for …

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handouts: 1. drugs sent worldwide the beginning of the influence of hours vremya nastupleniya the maximum time for the start of the effect the duration of the effects of an hour 1 2 3 4 nitroglitserin under the tongue 2-3 2-5 min. 0.2-0.5 transbukkal 2-3 30-60 min. 3-5 to drink 30-40 1-2 s 4-5 maz 15-60 1-2 s 3-8 plastyr 60-120 2-10 s 24hours isosorbide dinitrate under the tongue spray 1-2 2-5 min 1 sublingvo 2.5-10 20-40 min 1-2 to drink 10-60 1-3 s 2-6 isosorbide mononitrate to drink 20-50 2-3 s 10-12 deposits tablets 20-50 2-3 s 20-24 molsidomin to drink 20 30-60 min 4-6 2. determining the effectiveness of nitrate indicators: · angina attacks, islam weight reduction and …

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