gemorragik isitmalarni epidemiologiyasi vaftiziatriya

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kuydirgi yuqumli kasalliklar, epidemiologiya va ftiziatriya kafedrasi mudiri, t.f.n. dotsent yusupov shavkat raximbaevich o'zbekiston respublikasi sog'liqni saqlash vazirligi toshkent tibbiyot akademiyasi urganch filiali gemorragik isitmalar ko'pchilik yuqumli patogen mikroorganizmlar gemorragik belgilar: isitma, trombotsitopeniya, qon ivishining buzilishi va qon ketishi kabi simptomlar bilan kechadi bakterial sepsis (neisseria meningiditis) rikketsiozlar spiroxetozlar (leptospiroz) viruslar (filoviridae, arenaviridae, bunyaviridae va flaviviridae) gemorragik isitmalar epizootologiyasi kgi tashuvchisi kanalar hisoblanadi, bizning regionda asosan hyalomma va b.q. hyalomma dermacentor ixodes gemorragik isitmalar gemorragik isitmalar gemorragik isitmalar biologik qurol maqsadida sovet ittifoqi olimlari marburga va ebola viruslarini harbiy qurol maqsadida ishlab chiqishgan gemorragik isitmalar biologik qurol maqsadida eksperimental sharoitda primatlarda aerozol yo'li bilan kasallik chaqirish mumkinligi aniqlangan. bu viruslar juda kam dozada kuchli jararlash va o'lim darajasini chaqirishi mumkinligi tufayli biologik qurol sifatida qo'llashga qulay, ular yuqori xarorat chaqiradi hamda aholi o'rtasida vahima keltirib chiqaradi. bundan tashqari kasallikga qarshi zardob yo'q. virusli gemorragik isitmalar klinik belgilari vgi klinik sindromlari: …

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hliqqa qon ketishi gemorragik kon'yunktivit itsh (shok) laborator belgilar: leykopeniya yoki leykotsitoz trombotsitopeniya bioximik ko'rsatkichlar oshishi anemiya klinikasi klinikasi: denge gemorragik isitmasi petexial toshma teri osti qon quyilishi klinikasi oyoq ostida petexiyalar qon bosimini o'lchagan joyda petexiyalar klinikasi ichakdan qon ketishi oshqozonga qon quyilishi septik shakli 14 septitsemicheskaya chuma opredelyaetsya kak generalizovannoe zabolevanie soprovojdayusheesya virajennoy intoksikatsiey, vizvannoe y. pestis bez nalichiya predidushix pervichno-ochagovix porajeniy ( v chastnosti - limfaticheskix uzlov), a takje po krayney mere nekotoroe vremya i bez vtorichno-ochagovix proyavleniy. v soedinennix shtatax pervichnaya generalizovannaya (septitsemicheskaya) forma chumi obichno assotsiiruetsya s oxotoy i razdelkoy (snyatiem shkur) jivotnix . ma takje rassmotrim i vtorichno-generalizovannuyu (septitsemicheskuyu) formu chumi, kotoraya mojet razvitsya posle pervichnix form (bubonnoy ili pnevmonicheskoy). v soedinennix shtatax, 10-25% vsex sluchaev chumi yavlyayutsya pervichnoy septitsemicheskoy (generalizovannoy) formoy. na etoy kartinke vi mojete videt primer chumnoy septitsemii vizvannoy narusheniem koagulyatsii v sosudax paltsev ruk. septitsemik o'lat 15 obratite vnimanie na …

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ximicheskiy metod. viyavlenie spetsificheskix antitel v rsk i rdpa do 96% sluchaev podtverjdayut klinicheskiy diagnoz. viyavlenie virusnogo antigena v rnga, takje podtverjdaet dia-gnoz (100% sluchaev). leykopeniya so sdvigom vlevo, trombotsitopeniya (<100x10g/l), povi-shenie soe (orientirovanniy diagnoz). izolyatsiya virusa – 100% podtverjdenie klinicheskogo diagnoza. viyavlenie spetsificheskix immunoglobulinov (v diagnosticheskix titrax 1:800 i bolee obnarujivayutsya uje v samie pervie dni zaboleva-niya) klassa igm i igg (parnie sivorotki – obnarujenie vo 2-y probe pri otsutstvii v pervoy, ili 4-kratnoe narastanie titrov) – visokiy (uskorenniy) diagnosticheskiy priznak. polojitelniy rezultat ptsr v realnom rejime vremeni – 100% pod-tverjdenie diagnoza. gipoizostenuriya, mikrogematuriya. viyavlenie antigena iz patologoanatomicheskogo materiala dlya posmertnoy diagnostiki – 100% podtverjdenie diagnoza. ostroe zabolevanie, soprovojdayusheesya visokoy lixoradkoy i gemorragicheskim sindromom, xarakterizuyushimsya po krayney mere odnim iz sleduyushix priznakov:  petexialnaya sip;  krovoizliyaniya;  krovotecheniya (nosovie, matochnie, jeludochno-kishechnie, desnevie, reje - drugie);  trombotsitopeniya. • fakt kontakta s krovyu litsami, u kotorix otmecheni krovotechenie • …

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projivanie na territorii prirodnogo ochaga (gde registriruyutsya sluchai zabolevaniya lyudey ili jivotnix kkgl), i odnogo iz sleduyushego: ukus klesha; kontakt s kleshom ili s krovyu iz klesha; kontakt s krovyu bolnogo kkgl; kontakt s krovyu jivotnix, vozmojnix nositeley virusa (zaytsi i dr.).  epidemiologicheskaya svyaz s podtverjdennim sluchaem kkgl. zabolevanie, sootvetstvuyushee pred-polojeniyu i/ili veroyatnomu sluchayu, i kak minimum odno iz sleduyushego: izolyatsiya virusa; polojitelnaya ptsr v realnom vreme-ni; viyavlenie antitel klassa igm i igg metodom ifa; viyavlenie virusnogo antigena v rnga; viyavlenie antigena v patologoanatomicheskom materiale immunogistologicheskim metodom. etiotrop davosi patogenetik va simptomatik terapiya • 100-300 ml sivorotka yoki qon plazmasi (kasallikni boshdan o'tkazgan bemorlarniki); • loshadiniy gamma-globulin 5-7,5 ml (kattalarga); og'ir formalarida ketma-ket 3 kun qilinadi. gamma-globulin allergik reaktsiya chaqirishi mumkin; • kasallikning birinchi kunlari virusemiya, kuchli intoksikatsiya, qon quyilishi, leykopeniya, trombotsitopeniya, qon ivishi kamayishi kuzatilsa dezintoksikatsion terapiya, simptomatik va yurak qon-tomir sistemasi preparatlari; • kuchli qon ketishda qon …

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kuydirgi yuqumli kasalliklar, epidemiologiya va ftiziatriya kafedrasi mudiri, t.f.n. dotsent yusupov shavkat raximbaevich o'zbekiston respublikasi sog'liqni saqlash vazirligi toshkent tibbiyot akademiyasi urganch filiali gemorragik isitmalar ko'pchilik yuqumli patogen mikroorganizmlar gemorragik belgilar: isitma, trombotsitopeniya, qon ivishining buzilishi va qon ketishi kabi simptomlar bilan kechadi bakterial sepsis (neisseria meningiditis) rikketsiozlar spiroxetozlar (leptospiroz) viruslar (filoviridae, arenaviridae, bunyaviridae va flaviviridae) gemorragik isitmalar epizootologiyasi kgi tashuvchisi kanalar hisoblanadi, bizning regionda asosan hyalomma va b.q. hyalomma dermacentor ixodes gemorragik isitmalar gemorragik isitmalar gemorragik isitmalar biologik qurol maqsadida sovet ittifoq...

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