diphtheria and diphtheria toxoid
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powerpoint presentation diphtheria and diphtheria toxoid epidemiology and prevention of vaccine-preventable diseases national immunization program centers for disease control and prevention revised march 2002 1 diphtheria greek diphtheria (leather hide) recognized by hippocrates in 5th century b.c. epidemics described in 6th century c. diphtheriae described by klebs in 1883 toxoid developed in 1920s 2 corynebacterium diphtheriae aerobic gram-positive bacillus toxin production occurs only when c. diphtheriae infected by virus (phage) carrying tox gene if isolated, must be distinguished from normal diphtheroid 3 diphtheria clinical features incubation period 2-5 days (range, 1-10 days) may involve any mucous membrane classified based on site of infection anterior nasal tonsillar and pharynge...
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