clinical pharmacology of drugs

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activity no. 6 subject: " clinical pharmacology of drugs, activating and correcting metabolism, vitamins medicines " technology of training (practical employment) time: 270 minutes kind and form of the training session practical employment structure of the training session 1. the introductory part of 2. theoretical part 3. analytical part(organizer, tests and situational tasks) 4. the practical part (clinical practice) the purpose of training session explain to students the clinical pharmacologymedicinal products, activating and correcting metabolism, vitamins the student must know: - definition and classification of the medicines, activating and correcting the metabolism of vitamins; - pharmacological effects; - side effects of the medicines; - indications and contraindications; - methods for monitoring performance and security. the student must perform: - identify the indications and contraindications for assignment of medicines, modifying the metabolism of vitamins and coenzyme preparations. - pick up the dosage (once, daily, yearly dose) medicines based on pharmacokinetic and …

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nes; - the student maywork with literature, monographies and publications magazines; - the student mayadvise patients on rational acceptance of hp; training methods lecture, brainstorming, situation, view video methods, practice, chatting, learning game, organizer. form of education public, group work ("think in a pair-exchange opinions»), self. learning tools board-stand, flipchartd, movies, writing board, model, graphic, diagrams, schematics, control sheets, texts, checklists, tests, case patients. learning conditions audience with special equipment designed for group work (department, thematic study). monitoring and evaluation oral interview: a blitz-interview; written survey: test. technological card of educational employment stage of work and time ( 270 minutes) activities training trainees 1-stage 10 minutes 20 minutes 1.1. check notebooks and attendance 1.2. teacher explains the title of the topic, purpose, and expected results. introduces the lesson plan 1.2. tells the basic definitions on the subject and calls for independent work of literature; 1.3. acquaints with criteria of estimation; …

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sis of the results of the training session advance analysis of control issues. 3.4. does the job for independent work, evaluates perform practical skills evaluate yourself, each other. ask questions, write down the job 1. motivation - almost all diseases can lead to violations of the severity and intensity of metabolic processes in organs and tissues, which in turn affect its functional state. no doubt to correct these violations possible through etiological-pathogenesis therapy major diseases that cause metabolic disorders. however, adding in the complex therapy of medicines, modifying the metabolism contributes to the enhancement of the effectiveness of the therapy. knowledge of clinical pharmacology of these drugs and the ability to rationally apply necessary to achieve these goals. the ability to clarify testimony, their dosing schedule, monitor their effectiveness, to prevent the development of pd would enhance the effectiveness of the treatment of metabolic disorders. 2. intersubject and intrasubject communications …

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hould be noted, however, that the effectiveness of such drugs for various diseases of internal organs, particularly the heart, showed only small studies. therefore, their use is often referred to as curative with unproven effectiveness. to metabolic drugs for systemic use include biogenic stimulators: ginseng, pantokrin, eleuterokocca rhizome and roots, broken tree leaves, humisol*, royal jelly (apilak*), melatonin, etc. classification of metabolites by j.s. chekman and n.a. gorchakov 1. energy exchange substrates. 1.1. high-energy compound: atp, atp-long, adp, amp (fosfaden), guanozin, adenosine, inosine (riboksin), creatinephosphats (neoton) and others. 1.2. metabolites of glycolysis and pentose phosphate cycle: glyceraldehyde-3-phosphate, fructose-1, 6-diphosphate, hexose phosphate, phosphoenolpyruvate, etc. 1.3. the citric acid cycle substrates: succinic acid and derivatives (sodium succinate, potassium succinate, mexidol), malic acid and its derivatives (potassium malate, sodium malate), a-ketoglutaric acid, fumaric acid. 2. energy metabolism: coenzymes, nicotinamide, nicotinamide adenine dinucleotide, nicotinamide-adenine dinucleotide phosphate. 3. components of the respiratory chain: riboflavin, nicotinamide, …

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n-nitro-l-arginine, citrarginin, etc. 5.6. the gaba (gamma amino butyric acid) and its derivatives: sodium oxybutyrate, nootropil (piracetam), aminalonum, fenibut, pikamilon (noofen), etc. 5.7. other amino acids: methionine, tryptophan, lysine (the lysine escinat), etc. adenosine phosphate. adenosine phosphate (amp) component of the adenylic system; its biological role: • activation under anaerobic conditions of a number of enzymes of krebs-cycle, increased resynthesis of atp with the simultaneous inhibition of glycolysis; • as a purine nucleotide favours the synthesis of nucleic acids and protein synthesis therefore; • is a member of the most important respiratory coenzymes-migrate customers of electrons and protons in the primary chain of tissue respiration (nad, nadp and fad); • the power supply of the processes of synthesis-the predecessor of high-energy compounds (adp and atp formation occurs when the phosphorilation of amp); • participates in the regulation of carbohydrate metabolism. he is able to penetrate into the cells. in the …

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activity no. 6 subject: " clinical pharmacology of drugs, activating and correcting metabolism, vitamins medicines " technology of training (practical employment) time: 270 minutes kind and form of the training session practical employment structure of the training session 1. the introductory part of 2. theoretical part 3. analytical part(organizer, tests and situational tasks) 4. the practical part (clinical practice) the purpose of training session explain to students the clinical pharmacologymedicinal products, activating and correcting metabolism, vitamins the student must know: - definition and classification of the medicines, activating and correcting the metabolism of vitamins; - pharmacological effects; - side effects of the medicines; - indications and contraindications; - methods...

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