farmatsevtik maqsadda qo’llaniladigan suvga qo’yilgan gigienik talablar

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1522392941_70459.doc farmatsevtik maqsadda qo’llaniladigan suvga qo’yilgan gigienik talablar reja: 1. farmatsevtik maqsadda qo’llaniladigan suvni tayorlash usullari 2. farmatsevtik maqsadda qo’llaniladigan suvga qo’yilgan gigienik talablar 3. farmatsevtik maqsadda qo’llaniladigan suvning qo’llanish yo’llari the main objective in the design of the water storage and purified ras¬predeleniya system is to provide a constant movement of the water pipe, there is no dead zones that promote the growth of microorganisms and formation of biofilms on surfaces. modern storage and distribution systems mean by a recirculation system with odnonaprav¬lennym traffic flow and the ability to completely remove water from the pipeline. critical parameters in the storage and distribution of purified water are: - temperature; · the movement of water and its velocity; · pressure; · materials of pipelines and storage tanks. distribution and storage of purified water according to gmp regulation should be carried out at temperatures that prevent the growth of microorganisms - above …

production. the main materials used are: · polymer materials like pp and pvdf (from the english poly¬propylene · polypropylene, polyvinylidenejluoride.), etc., the most commonly used in -designing cold water distribution circuits purified. - stainless steel 316 l with the surface roughness of not more than 0,8 ra. storage and distribution of water for injections · water storage and distribution problem for injection is considered d. dismore (firm steris) in the journal "technology of cleanliness" №2 / 2001. when you create a water storage and distribution systems for injection have to comply with the following requirements: · the capacity of the tank should be such as to satisfy the user's requirements to the maximum one-time consumption of water · minimum installation performance should take into account any future user requirements · water quality in its delivery to the point of use. control parameters of water: • temperature, • pressure, · conductivity, …

growth of microorganisms must be minimized; 2) changes in water temperature must be kept to a minimum; 3) during the treatment should be provided in contact with all surfaces. (2) 2. w. whyte. cleanroom technology. new york. 2002. suvning tayyorlanishi. sanoatning elektron, kimyoviy, farmatsevtika va boshqa sohalarida ko’pgina texnologik jarayonlarda yuqori darajada toza hisoblangan suvdan foydalaniladi. suvning o’ta toza bo’lishi va uni olishning maxsus texnologiyasi dori vositalarini ishlab chiqarishda (in’ektsiya uchun suv va tozalangan suv) zarurdir. tozalangan suvdan turli maqsadlarda foydalanilsada, ammo uni olishning usullari bir xil tartibga asoslanadi. bunda farmatsevtik maqsadlarda ishlatiladigan toza suvni olish tartibi namuna qilib belgilangan. farmatsevtik maqsadlarda ishlatiladigan suv. farmatsevtik maqsadlarda ishlati-ladigan suv dori vositalarining xavfsizligini ta’minlaydigan muhim elementlarga kiradi. uning sifati davlat farmakopiyasiga kiritilgan farmakopiy modda (fs) bilan qat’iy belgilangan. fs 42-2619-97 “tozalangan suv” va fs 42-2619-97 “in’ektsiya uchun suv”. tozalangan suvdan quyidagilarda foydalaniladi: in’ektsiya uchun ishlatilmaydigan dorivor vositalarni tayyorlashda; bug’ hosil qilishda; sanitar …

tabiiy suv tarkibida har xil aralashmalar bo’lishi mumkin: mexanik zarralar (erimaydigan organik va noorganik aralashmalar), eriydigan moddalar ( noorganik tuz-lar, kaltsiy, magniy, natriy, xlor ionlari, oltingugurt, ko’mir kislotalari va boshqalar); kimyoviy faol bo’lmagan eriydigan gazlar (kislorod, azot); kimyoviy faol bo’lgan eriydigan gazlar (uglerod dioksidi, ammiak); mikroorganizmlar (jumladan, ko’z ilg’aydiganlar, mog’or zamburug’lari, suv o’tlari va tsistalar va h); bakteriyali endotoksinlar ( grammanfiy mikroorganizmlarning hujayra devorlaridagi lipopoli-saxaridlar); organik moddalar (tabiiy organik moddalar – gumina kislota va b. hamda ifloslantiruvchi organik moddalar – sanoat chiqindilari, o’g’itlar, pistitsitlar va b.); kolloidlar (organik moddalar bilan birikib kompleks birikmalar hosil qiluvchi temirning fe2o3 x u h2o, kremniyning sio2 x y h2o, alyuminiyning al2o3 x y h2o birikmalari); qolgan dezinfiktsiyalovchi moddalar (xlor, xlor kislotasi, gipoxlorit – ion, xloraminlar va b.). asos suv “ichimlik suvi” san pin 2.1.4.1074.01ga muvofiq ichimlik suvi talablariga javob berishi shart. “suv ta’minotining markazlashgan sistemasidagi ichimlik suvining sifati gigienik talablarga javob berishining sifat nazorati”. …

bda aralashmalarni yo’qotishga yo’naltirilgan dastlabki tozalash bosqichlariga. dastlabki tayyorgarlik – bu sifatli tozalangan suvni olish uchun qilinadigan operatsiyalar majmuidir. normativ talablarga mos keladigan suvni olish bu so’nggi bosqich sanaladi. filtrlash.suvni qayta ishlash sistemasida filtratsiya texnologiyasi muhim rol o’ynaydi. turli usullarda qo’llash uchun filtrlash qurilmalarining juda ko’p turlari ishlab chiqarilmoqda. qismlarni g’alvirdan o’tkazish darajasiga ko’ra ular bir –biridan tubdan farq qiladi. yirik donalarni (antratsit donachalari, kvarts, qum) filtrlovchi va mayda donachalarni filtrlovchi membran filtrlar. qurilma va sistemalarning o’zaro joylashishi texnologik jarayonda filtrlash uskunalarining qo’llanish joyi va turiga ko’ra o’zgaradi. zamonaviy filtrlash sistemasi 3 va 5 tsiklli ish rejimiga ega, ya’ni ular avtomatik ravishda (nazorat dasturi asosida) ishlashga va qo’lda boshqarishga moslangan. texnologik ish rejimida filtrlash qurilmasi quyidagilarni bajaradi: suvni tozalangan holda olish, filtr oraliqni to’g’ri va qayta tozalash. bu rejimdan regeneratsiya talab qilmaydigan (ko’p qavatli filtrlar, birm asosida temirsizlantiruvchi filtrlar, aktivlashtirishgan ko’mirli filtrlar) sepuvchi qurilmada foydalaniladi. ishning besh tsiklli rejimida suvni …

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1522392941_70459.doc farmatsevtik maqsadda qo’llaniladigan suvga qo’yilgan gigienik talablar reja: 1. farmatsevtik maqsadda qo’llaniladigan suvni tayorlash usullari 2. farmatsevtik maqsadda qo’llaniladigan suvga qo’yilgan gigienik talablar 3. farmatsevtik maqsadda qo’llaniladigan suvning qo’llanish yo’llari the main objective in the design of the water storage and purified ras¬predeleniya system is to provide a constant movement of the water pipe, there is no dead zones that promote the growth of microorganisms and formation of biofilms on surfaces. modern storage and distribution systems mean by a recirculation system with odnonaprav¬lennym traffic flow and the ability to completely remove water from the pipeline. critical parameters in the storage and distribution of purified water are: ...

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