allergiya i beremennost

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pishevaya allergiya – sostoyanie povishennoy chuvstvitelnosti organizma k pishevim produktam, kotoroe razvivaetsya pri narushenii funktsionirovaniya immunnoy sistemi allergiya i beremennost rost allergicheskix zabolevaniy otmechaetsya ne tolko sredi naseleniya voobshe, no i sredi beremennix. po poslednim dannim rasprostranennost az sredi beremennix kolebletsya ot 5% do 20%. osnovnie problemi allergicheskix zabolevaniy, voznikayushie pri beremennosti: vliyanie beremennosti na techenie allergicheskix zabolevaniy vliyanie allergicheskix zabolevaniy na techenie beremennosti vliyanie allergicheskix zabolevaniy na razvitie ploda osobennosti taktiki vedeniya allergicheskix zabolevaniy i vedeniya beremennosti u jenshin, stradayushix allergiey videlyayut tri tipa vliyaniya beremennosti na techenie allergii : - beremennost nikak ne vliyaet na techenie allergii - na fone beremennosti nastupaet remissiya allergicheskix zabolevaniy - na fone beremennosti otmechaetsya obostrenie allergicheskogo zabolevaniya absolyutno dokazano, chto nalichie allergicheskix zabolevaniy ne yavlyaetsya protivopokazaniem dlya beremennosti i rojdeniya rebenka. neobxodimo uchitivat anatomo-fiziologicheskie osobennosti funktsionirovaniya razlichnix organov i sistem vo vremya beremennosti s tselyu naznacheniya adekvatnoy terapii i profilaktiki obostreniy allergicheskix …

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shenie pronitsaemosti legochnix kapillyarov povishenie gastroezofagealnogo reflyuksa pri beremennosti mojet provotsirovat pristup udushya dopolnitelnaya stressovaya nagruzka na organizm beremennoy zatrudnenie nosovogo dixaniya (rinit beremennoy i dr.) vozmojno povishenie chastoti obostreniya angiootekov iz-za povisheniya ob'ema tsirkuliruyushey krovi u beremennix, chto mojet privodit k snijeniyu kontsentratsii s1 ingibitora. allergicheskiy rinit 20% naseleniya planeti stradayut ar, ~ 50% beremennix – gormonalniy rinit beremennix osobennosti klinicheskogo techeniya allergicheskix zabolevaniy pri beremennosti differentsialnie priznaki allergicheskogo rinita i neallergicheskogo rinita priznak allergicheskiy rinit neallergicheskiy rinit prichini allergeni: bitovie, epidermalnie, piltsevie, pishevie, insektnie, lekarstvennie anatomicheskie defekti, zabolevaniya nosoglotki, rezkie zapaxi, rezkie temperaturnie izmeneniya, postoyanniy priem dekongestantov, beremennost, gipotireoz, pervichnaya diskineziya resnichek, ids, granulomatoz vegenera allergologicheskiy anamnez polojitelniy otritsatelniy kojnie testi s allergenami polojitelnie otritsatelnie, vo vremya beremennosti ne provodyatsya tsitologicheskoe issledovanie slizistoy nosa soderjanie eozinofilov v mazke bolee 2-4% eozinofili otsutstvuyut. pri infektsionnom rinite – visokoe soderjanie neytrofilov uroven obshego ige v sivorotke krovi povishen norma nalichie …

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rati s dokazannoy teratogennostyu v eksperimente i klinike. protivopokazani pri beremennosti. neblagopriyatnie vozdeystviya lekarstv na plod embriotoksicheskoe (gibel embriona i prerivanie beremennosti). teratogennoe (razvitie vrojdennix urodstv u ploda). fetotoksicheskoe (negativnie vozdeystviya na plod, ne soprovojdayushiesya razvitiem teratogennix effektov). farmakoterapiya allergicheskogo rinita pri beremennosti preparati kromoglitsievoy kisloti antigistaminnie preparati mestnogo deystviya (levokabastin, azelastin) topicheskie (nazalnie) steroidi: mometazon furoat (nazoneks), flutikazona propionat nazalnie kortikosteroidi ustranenie simptomov i obostreniya umenshayut vospalenie slizistoy obolochki ugnetenie reaktsiy pozdney fazi, isxodnoy nazalnoy giperchuvstvitelnosti 1 umenshayut chislo tuchnix kletok v slizistoy ustranenie ostroy allergicheskoy reaktsii 2 ugnetayut aktivnost jelez i sosudistuyu pronitsaemost vizivayut vazokonstriktsiyu 3 bezopasnost flutikazona propionat i mometazona furoat (nazoneks) u osobix grupp patsientov priem igks vo vremya beremennosti ne vizival pobochnogo vozdeystviya na organizm materi i techenie beremennosti1 igks ne okazival vliyaniya na rost i razvitie ploda1 1. e.k. ellegard, clin otolaryngol. 2001, 2001, 26, 394-400 beremennie jenshini doljni vozderjatsya ot primeneniya nazalnogo spreya …

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96; 97:198 0 5 10 15 20 17 17 17 17 slide #17 because hpa-axis suppression is one of the most sensitive indices of systemic exposure to glucocorticoids, an extensive evaluation of the effects of nasonex on plasma cortisol levels was undertaken. results from several studies have documented the general absence of hpa-axis effects following nasonex administration, consistent with its extremely low bioavailability. in a recent clinical study, brannan et al assessed 24-hour plasma cortisol area-under-the-concentration curve (aucs) in healthy volunteers.1 as shown in this slide, single doses of mometasone furoate administered intranasally at 11 p.m. (to maximize the potential effect on the hpa-axis) at doses of 1, 2, and 4 mg produced no systemic effects. no effect of nasonex on cortisol secretion was seen even at doses up to 20 times (4000 g) the usual dose (200 g). 1. brannan md, seiberling m, cutler dl, et al. lack of …

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elya beremennosti) – eritematoznie papuli. polimorfnaya sip beremennix – zudyashie otechnie papuli i blyashki. pupp-sindrom (pruritic urticarial papules and plagues of pregnancy) - (0,5% beremennix). lokalizatsiya – jivot, oblast striy. zud beremennix (pruritis gravidarum) (2,5% beremennix, 2-3 trimestr). patologicheskix elementov net. patogenez – narushenie funktsiy pecheni. atopicheskiy dermatit ~ 1-50% beremennix 25% - uluchshenie 25% - bez izmeneniy ~ 50% - uxudshenie lechenie ustranenie triggernix faktorov narujnaya terapiya sistemnie preparati narujnaya terapiya neftorirovannie topicheskie ks (elokom, lokoid) - ne bolee 10 dney topicheskie ag preparati dimetidin (fenistil gel) uxod za kojey antigistaminnie preparati klemastin (tavegil). ne naznachaetsya v pervom trimestre beremennosti. gnoynie oslojneniya ad makrolidi, tsefalosporini. absolyutno protivopokazani tetratsiklini i aminoglikozidi allergodiagnostika i beremennost spetsificheskie allergologicheskie metodi issledovaniya i testi, provodimie in vivo (testi s ispolzovaniem allergenov, mediatorov, nespetsificheskix razdrajiteley, fizicheskoy nagruzki i dr.) pri beremennosti zapresheni, poskolku mogut privesti k obostreniyu zabolevaniya i otrazitsya na sostoyanii beremennoy i ploda …

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pishevaya allergiya – sostoyanie povishennoy chuvstvitelnosti organizma k pishevim produktam, kotoroe razvivaetsya pri narushenii funktsionirovaniya immunnoy sistemi allergiya i beremennost rost allergicheskix zabolevaniy otmechaetsya ne tolko sredi naseleniya voobshe, no i sredi beremennix. po poslednim dannim rasprostranennost az sredi beremennix kolebletsya ot 5% do 20%. osnovnie problemi allergicheskix zabolevaniy, voznikayushie pri beremennosti: vliyanie beremennosti na techenie allergicheskix zabolevaniy vliyanie allergicheskix zabolevaniy na techenie beremennosti vliyanie allergicheskix zabolevaniy na razvitie ploda osobennosti taktiki vedeniya allergicheskix zabolevaniy i vedeniya beremennosti u jenshin, stradayushix allergiey videlyayut tri tipa vliyaniya beremennosti na techenie ...

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