licensure model exam for pharmacy

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eherqa licensure model exam for pharmacy time allowed: 3:00 hr name ___________________________________id no ________________section_______ multiple choice questions choose the letter of correct answer and write it in space provided on separate sheet. 1. erythromycin suspension is very viscous and, therefore, difﬁcult to pour from the original container into the dispensing bottles. it is also stored in a refrigerator. prior to dispensing the desired volume of the suspension, the original container is shaken rigorously to make it easier to pour into the dispensing bottle. why is it easier to pour after shaking? a. suspensions like erythromycin are described a shear-thinning systems. b. when it is shaken, it is subjected to higher forces, which, in turn, increase the rate of shear. c. the increase in the rate of shear lower the viscosity of the suspension and enable it to ﬂow easily. d. all e. none 2. how does the increase in the …

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he emulsion is o/w type. e. none 4. regarding the rate of sedimentation of pharmaceutical suspensions designed for oral administration, which of the following statements are true? a. the rate of sedimentation is increased as the diameter of the dispersed drug particles is increased. b. the rate of sedimentation is increased as the viscosity of the continuous phase is increased. c. the rate of sedimentation may be increased by centrifugation. d. all e. none 5. sodium sulfate…………………….……………5gm liquid paraffin…………………………………50gm cherry syrup q.s….…………………………….120gm liquid paraffin and cherry syrup are two immiscible liquids. what ingredient would you need to formulation these preparation a. suspending agents b. viscosity inducing agents c. emulsifying agents d. solvent e. none 6. which equation is used to predict the stability of a drug at room temperature from experiments at increased temperatures? a. stoke’s equation b. arrhenius equation c. michaelis–menten equation d. henderson–hasselbalch equation e. noyes–whitney equation 7. …

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hydrolysis. b. oxidation c. photo-degradation d. lower temperature e. ph 10. which of the following solvents cannot be ingested orally with a formulation? a. ethanol b. glycerin c. propylene glycol d. polyethylene glycol 400 e. none 11. __________are liquid preparations which comprise nitrocellulose or pyroxylin dissolved in a solvent mixture with or without a medicinal agent and are highly volatile and highly flammable and care should be taken to label any preparation appropriately. a. colloidons b. lotions c. elixirs d. linctuses e. none 12. converting chloramphenicol (soluble form) to chloramphenicol palmitate (insoluble form) a. makes the preparation more palatable b. increase the drugs absorption c. makes the preparation more permeable d. makes the preparation more soluble e. none 13. chloroquine is common drug for the treatment of malaria. it is a substance that is susceptible to photodegradation. so, which glass would you use as a container for these drug a. …

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he following formula. you prepare this prescription and notice that the suspension settles extremely fast, such that within 30 seconds it has completely settled. rx tracmicin: 250 mg/ml 2% methylcellulose: 10 ml vanillin (ﬂavoring agent): 0.2% water qs ad: 100 ml which of the following techniques could be used to decrease the rate of settling? a. you could increase the concentration or volume of methycellulose used in the formulation. b. you could add a viscous liquid, such as glycerin, to this suspension. c. you could decrease the particle size by levigating the tracmicin in a mortar and pestle. d. all of the above. 17. all of the following are examples of irrational use of drugs except b. non-compliance with prescriptions c. self-medication with prescription drugs d. over use and misuse of antibiotics e. high adherence with medication 18. ______ is part of prescription which contains direction to be given for …

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agedy in pharmaceutical history? a) tolbutamide b) thalidomide c) diethystilbestrol d) propylthiouracil 24. how much ppf (procaine penicillin fortified) will be discarded from the last vial if 600,000 iu of the drug is administered bid for 7 days. the iu of the drug is 4 miu. a) 0.4 miu b) 5.4 miu c) 3.6 miu d) none 25. indicate which of the following interactions might be expected to lead to an increased drug absorption: a. adsorption of drugs onto antacids and charcoal b. interaction of bile salts with neomycin, kanamycin, and nystatin c. complexation of itraconazole with hydroxypropyl-β-cyclodextrin d. chelation of tetracyclines with dicalcium phosphate in tablet dosage form e. complexation of phenobarbitone and polyethylene glycol 4000 26. which one of the following statements is wrong about tetracyclines? a. they are ionized over entire gi ph b. they are too large to pass through aqueous filled pores in membrane. c. …

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eherqa licensure model exam for pharmacy time allowed: 3:00 hr name ___________________________________id no ________________section_______ multiple choice questions choose the letter of correct answer and write it in space provided on separate sheet. 1. erythromycin suspension is very viscous and, therefore, difﬁcult to pour from the original container into the dispensing bottles. it is also stored in a refrigerator. prior to dispensing the desired volume of the suspension, the original container is shaken rigorously to make it easier to pour into the dispensing bottle. why is it easier to pour after shaking? a. suspensions like erythromycin are described a shear-thinning systems. b. when it is shaken, it is subjected to higher forces, which, in turn, increase the rate of shear. c. …

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