educational-methodical recommendation (case - step)

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ministry of health of the republic of uzbekistan tashkent medical academy department of clinical pharmacology case - technology "clinical pharmacology of drugs used at gastrointestinal disease" educational-methodical recommendation (case - step) is designed for teachers and students of v-year medical institutions tashkent – 2015 educational abstract the subject: "clinical pharmacology" topic: "clinical pharmacology of drugs used at gastrointestinal disease" the purpose of this case: giving students knowledge of the basic principles and umeneniyu individual selection of effective and safe drugs that affect the motor and secretory function of the gastrointestinal tract with the pharmacodynamics, pharmacokinetics, side effects, and features action and its dependence on various factors (pregnancy, age, the functional state of metabolism and elimination expected learning outcomes - based on the results of work with a case students acquire the following knowledge and skills :. • basic mechanisms of digestive diseases • modern classification of drugs affecting the motor-evacuation …

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em and its solution; for the successful solution of this case study, students must master in advance the following knowledge and skills: 1. identification of drugs that affect the motor and secretory function of the gastrointestinal tract and their characteristics 2. classification of drugs that affect the motor and secretory function of the gastrointestinal tract 3. the mechanism of action of the main groups of drugs that affect the motor and secretory function of the gastrointestinal tract 4. indications and contraindications for therapy drugs that affect the motor and secretory function of the gastrointestinal tract 5. side effects of drugs that affect the motor and secretory function of the gastrointestinal tract and assistance measures 6. interactions of drugs that affect the motor and secretory function of the gastrointestinal tract with other drugs 7. monitoring the effectiveness and safety of medicines that affect the motor and secretory function of the gastrointestinal …

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e formation of acid. antacids and adsorbents - neutralize hydrochloric acid in the stomach and 12p. to-ke, without affecting its products. these include compounds of alkaline earth metals, sodium bicarbonate, calcium and magnesium carbonates, magnesium trisilicate, aluminum hydroxide, bismuth preparations and others. recent addition of weak hydrochloric acid neutralizing action, have a pronounced absorption properties, as well as bactericidal against bacterial infections campo . besides hydrochloric acid neutralizing antacid action and adsorbents also provide the following effects: • normalize the motor function of the stomach and 12p. intestine due to a more rapid opening of the pylorus and the expulsion of intestinal cavity in the "middle" of gastric contents, which reduces the intragastric and intraduodenal pressure eliminates pathological reflexes. a related analgesic effect. • tsitoprotektornoe effect due to the stimulating effect on the production of prostaglandins, astringent and protective action (magnesium trisilicate, bismuth preparations). • the inactivation of pepsin by …

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relief of heartburn pain. given its ability to cause the so-called "acid rebound" sodium bicarbonate is not used for a course of treatment giperatsidnyh states. b) a slow-or nonabsorbable: magnesium trisilicate, aluminum hydroxide, calcium phosphate, bismuth carbonate and others. they are insoluble in water, slightly absorbed from the gastrointestinal tract, and do not cause changes aar. their effects develop slowly but last longer. for the duration of action are distinguished: a) short-acting (from 5-10 to 20-30 min.). this - sodium hydrogencarbonate, calcium and magnesium carbonates, magnesium oxide. b) a long-acting formulations: magnesium trisilicate, aluminum hydroxide. lasts for 3-4 hours on average. on the severity of the effect: in order of decreasing effect preparations are arranged as follows: magnesium oxide, aluminum hydroxide, calcium carbonate, magnesium trisilicate, sodium bicarbonate. antacid action also depends on the time of assignment with respect to food intake, dosage forms, combinations with other drugs. for example, antacid …

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and magnesium to provide high neutralizing activity and cytoprotective effect. the latter is due the fact that the aluminum ions stimulate slizeobrazovanie. is available in tablets and in the form of a slurry. maalox, 70 differs from the conventional maalox high content of active ingredients that provides a higher effect of neutralizing (70 meq). in addition, the release suspension maalox plus (canada) in addition to containing aluminum and magnesium hydroxide semitikon. aluminum hydroxide is used in the form of a 4% suspension in water. assign it 1-2 teaspoons 4-6 p / day. almagelum- complex preparation composed of aluminum hydroxide, magnesium oxide, and d-sorbitol. has antacid, absorbent and protective properties. d-sorbitol promotes bile secretion and looser bowel. appoint 1-2 dosage spoon 4-6 times a day for 30 minutes. before a meal (or at 1.5 hr. after meals) and bedtime. almagelum-a also contains benzocaine (0.1 g. per 5 ml of gel) fosfalyugel …

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ministry of health of the republic of uzbekistan tashkent medical academy department of clinical pharmacology case - technology "clinical pharmacology of drugs used at gastrointestinal disease" educational-methodical recommendation (case - step) is designed for teachers and students of v-year medical institutions tashkent – 2015 educational abstract the subject: "clinical pharmacology" topic: "clinical pharmacology of drugs used at gastrointestinal disease" the purpose of this case: giving students knowledge of the basic principles and umeneniyu individual selection of effective and safe drugs that affect the motor and secretory function of the gastrointestinal tract with the pharmacodynamics, pharmacokinetics, side effects, and features action and its dependence on various factors (pregna...

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