assessment of metabolic disorders in women in the postmenopausal period

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microsoft word - cajecs, volume 2,6, issue 6 central asian journal of education and computer sciences (cajecs) volume 2 issn: 2181-3213 february, 2024 13 № 6 issue 6 assessment of metabolic disorders in women in the postmenopausal period sabirova munisa1, mukhamedova nurkhon2 1emu senior lecturer doctor of medical sciences (phd), e-mail: sabirovamunisa1968@gmail.com tashkent, uzbekistan. 2tma professor (dcs) e- mail: nurhon 6969@mail.ru tashkent, uzbekistan. abstract: this article examines the determination of the characteristics of changes in carbohydrate and lipid metabolism, changes in the lipid transport system in women with metabolic syndrome in the postmenopausal period. key words: carbohydrate metabolism, postmenopausal period, lipid metabolism, metabolic syndrome, lipid profile, lipid transport system, free fatty acid content. the nature of changes in carbohydrate metabolism in postmenopausal women with metabolic syndrome. aim: identifying features changes in carbohydrate metabolism in postmenopausal women with metabolic syndrome. research materials, main part: to measure blood glucose levels, the colorimetry …
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ournal of education and computer sciences (cajecs) volume 2 issn: 2181-3213 february, 2024 14 № 6 issue 6 pituitary gland, which is responsible for the production of adrenocorticotropic hormone. this imbalance in the neuroendocrine system is called "postmenopausal pituitary gland." when a stress test was performed, postmenopausal women with metabolic syndrome found that blood insulin levels were on average 38.0% higher compared to a group of women without this syndrome. this difference is statistically significant (p 0.05). estrogen levels decline gradually during the postmenopausal period, which can lead to the accumulation of fat, especially free fatty acids. these fatty acids stimulate the pancreas to produce insulin and reduce its clearance in the liver, which contributes to increased hyperinsulinemia. they can also reduce insulin's ability to bind to its receptors and slow down the absorption and use of glucose. the state of lipid metabolism in postmenopausal women with metabolic syndrome. in …
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e (ms). these women were found to have higher than normal levels of total cholesterol, triglycerides, hdl, ldl and vldl. fig 2. lipidograms in women with ms in the postmenopausal period the concentration of total cholesterol in the blood of females with ms during the postmenopausal period was higher than these values relative to the comparison group by 22% and averaged 6.24±0.33 mmol/l (p<0.05). the number of triglycerides was more than 2 times higher than the baseline values (p<0.05). hdl concentrations had similar values. lipid profile indicators (mmol/l) in women with ms in the postmenopausal period. 0 1 группа сравнения, n=18 женщины с мс в постменопаузе, n=82 0,33 0,94*** 0 2 4 6 8 общий холестерин триглицериды лпвп лпнп лпонп 5,13 1,42 1,28 3,34 0,71 6,24** 3,16*** 1,22 3,89 1,18* группа сравнения, n=18 женщины с мс в постменопаузе, n=82 central asian journal of education and computer sciences (cajecs) volume 2 …
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triglycerides and cholesteryl esters relative to the number of apoproteins. this increase in the concentration of vldl in females with ms during postmenopause in the blood plasma may be based on the high concentration of triglycerides and their synthesis in the liver under the influence of lipoprotein lipase. central asian journal of education and computer sciences (cajecs) volume 2 issn: 2181-3213 february, 2024 18 № 6 issue 6 results of changes in the lipodogram during postmenopause in the presence of ms are related not only to changes in hormonal levels, but also to physiological changes in liver activity. indicator in the blood lipoprotein spectrum in postmenopausal women with ms.to assess the ratio of atherogenic and antiatherogenic lipoproteins, various calculation coefficients are used. the simplest and most effective is the cholesterol coefficient put forward by a.n. klimov, which is determined from the total cholesterol and a-alipoprotein cholesterol (hdl cholesterol):or as the …
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cline, risk factors for developing metabolic disorders increase. estrogens have a protective effect on lipid metabolism in the body in the following way: they increase the production of large lipoproteins rich in triglycerides, as well as the level of total triglycerides in the blood. estrogens also lower ldl levels in the blood by increasing the number of ldl receptors in the liver, causing them to be metabolized more quickly. central asian journal of education and computer sciences (cajecs) volume 2 issn: 2181-3213 february, 2024 19 № 6 issue 6 in addition, estrogens can slow hepatic triglyceride lipase activity and increase hdl levels by slowing their removal from the bloodstream. such effects may be related to intracellular cholesterol regulation and the effects of sterol-binding regulatory protein- almost all women with metabolic syndrome (ms) in the postmenopausal period have abnormalities in the blood lipid profile, and only in a very small part …

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microsoft word - cajecs, volume 2,6, issue 6 central asian journal of education and computer sciences (cajecs) volume 2 issn: 2181-3213 february, 2024 13 № 6 issue 6 assessment of metabolic disorders in women in the postmenopausal period sabirova munisa1, mukhamedova nurkhon2 1emu senior lecturer doctor of medical sciences (phd), e-mail: sabirovamunisa1968@gmail.com tashkent, uzbekistan. 2tma professor (dcs) e- mail: nurhon 6969@mail.ru tashkent, uzbekistan. abstract: this article examines the determination of the characteristics of changes in carbohydrate and lipid metabolism, changes in the lipid transport system in women with metabolic syndrome in the postmenopausal period. key words: carbohydrate metabolism, postmenopausal period, lipid metabolism, metabolic syndrome, lipid profile, li...

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