туберкулёз эпидемиологияси, патогенези ва иммунитет феноменлари

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слайд 1 туберкулёз эпидемиологияси, патогенези ва иммунитет феноменлари. бухоро давлат тиббиёт институти фтизиатрия кафедраси туберкулёз сурункали юқумли касаллик организмдаги барча аъзо ва тизимларни зарарлайди ҳамда оғир асоратларга олиб келади * туберкулёз глобал масштабда дунё аҳолисини учдан бир қисми (2 миллиарддан ортиқ) туберкулёз билан зарарланган * * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of these deaths occur in the developing world. staggeringly, for a disease many of us believed would disappear in our lifetime, tb is estimated to be the commonest cause of death of young women worldwide. worse still, but at the same …

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f young women worldwide. worse still, but at the same time providing cause for hope, these deaths are preventable. however, persistent poor practice in many countries is raising the spectre of multi-drug resistant (mdr) tb. this form of tb, if it became widely established, would make the control of the disease beyond the financial capacity of many countries. туберкулёз глобал масштабда дунёда ҳар йили туберкулёздан 4 миллион одам ўлади: аёллар – 900 000 болалар – 300 000 * * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of these deaths occur in the developing world. …

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g world. staggeringly, for a disease many of us believed would disappear in our lifetime, tb is estimated to be the commonest cause of death of young women worldwide. worse still, but at the same time providing cause for hope, these deaths are preventable. however, persistent poor practice in many countries is raising the spectre of multi-drug resistant (mdr) tb. this form of tb, if it became widely established, would make the control of the disease beyond the financial capacity of many countries. туберкулёз глобал масштабда туберкулёздан ҳар куни 5000 одам ўлади – лекин бу касалликни ҳозирги вақтда давоси бор ва тузалади * * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some …

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most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of these deaths occur in the developing world. staggeringly, for a disease many of us believed would disappear in our lifetime, tb is estimated to be the commonest cause of death of young women worldwide. worse still, but at the same time providing cause for hope, these deaths are preventable. however, persistent poor practice in many countries is raising the spectre of multi-drug resistant (mdr) tb. this form of tb, if it became widely established, would make the control of the disease beyond the financial capacity of many countries. инфекцияланиш мазкур йил давомида ахоли орасида туберкулин синамалари ўтказилганда синама мусбат бўлганларнинг % кўрсаткичи касалланиш – мазкур …

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йлиги тбнинг оилавий ўчоғи туберкулёз патогенези маҳаллий ҳимоя: мукоцилиар клиренс фагоцитоз мбт полинуклеар фагоцит туберкулёз патогенези фагоцитоз 3 даврдан иборат: i давр – макрофаг рецепторлари орқали ҳужайра мембранасига мбтнинг бирикиши давоми ii давр мбт+макрофаг макрофаг деворларининг инвагинацияси фагосома ҳосил бўлиши давоми iii давр фагосома ишлаб чиқарадиган ферментлар таъсирида мбт лар парчаланади ва емирилади туберкулёз патогенези - мбт м л фл i ii iii туберкулёз патогенези ig синтези b - л мбт парчалари il – 1 t - л il – 2 макрофаглар миграцияси мбт га нисбатан ферментлар фаоллигининг кучайиши ф туберкулёз патогенези т – лимфоцитлар т helper т кiller т supressor + м м м гзт специфик ўзгаришнинг морфологик кўринишлари : экссудация пролиферация альтерация некроз жараёнларидан бири устунлик қилиши мумкин специфик ўзгаришнинг морфологик кўринишлари : туберкулёз бўртмачаси гранулёмалар турли ўлчамдаги ўчоқлар, шикастланиш соҳалари туберкулёз касаллигининг грануляцион тўқимасида эпителиоид ҳужайралар лимфоид элементлар пирогов-лангханс гигант ҳужайралари яллиғланиш жараёнидаги морфологик ўзгаришлар лимфоид ҳужайралар …

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слайд 1 туберкулёз эпидемиологияси, патогенези ва иммунитет феноменлари. бухоро давлат тиббиёт институти фтизиатрия кафедраси туберкулёз сурункали юқумли касаллик организмдаги барча аъзо ва тизимларни зарарлайди ҳамда оғир асоратларга олиб келади * туберкулёз глобал масштабда дунё аҳолисини учдан бир қисми (2 миллиарддан ортиқ) туберкулёз билан зарарланган * * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of these deaths occur in the...

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