xayz oldi sindromi va mastopatiyaning oldini olish xamda davolashning zamonaviy usullari

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slayd 1 1 abu ali ibn sino nomidagi buxoro davlat tibbiyot instituti 2- akusherlik va ginekologiya kafedrasi «xayz oldi sindromi va mastopatiyaning oldini olish xamda davolashning zamonaviy usullari» tuzuvchilar: katta assistent: xamdamova m.t. assistent: raxmatullaeva m.m. assistent: ashurova n.g. assistent: juraev n.b. xayz kurishdan oldin yuzaga keladigan va nerv-psixik, vegeto-tomir, endokrin va somatik uzgarishlar bilan namoen buladigan simptomokompleksdir , xayz oldi sindromi xayz oldi sindromi yuzaga kelish nazariyalari: gormonal (giperestrogeniya (1931g), progesteron etishmovchiligi, gprl) «suv intoksikatsiyasi» teoriyasi allergik psixosomatik buzilishlar xozirgi vaktda xayz oldi sindromi patogenezida mns neyropeptidlari ( dofamin, noradrenalin) almashinuvining va neyroendokrin jarayonlarining buzilishlari asosiy urin egallaydi deb talkin kilinyapti. 3 25 – 75 % aellarda uchraydi shulardan 35 % i dori vositalarini kullaydi gprl bor aellarining 50 % ida uchraydi 30 eshgacha xayz oldi sindromi 20 %, 30 eshdan keyin xar 2 aeldan birtasida uchrashi mumkin menopauza oldi davrga borib xayz oldi sindromiga chalingan aellarda klimakterik buzilishlar …

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m zabolevaniem molochnix jelez yavlyaetsya mastopatiya ili fibrozno-kistoznaya bolezn. mastopatiya fibrozno-kistoznaya bolezn, xarakterizuyushayasya narusheniem sootnosheniy jelezistogo i soedinitelnotkannogo komponentov, shirokim spektrom proliferativnix i regressivnix izmeneniy tkaney molochnoy jelezi aktualnost problemi mastopatiy chastota vstrechaemosti mastopatiy v obshey populyatsii– 30-40%,u jenshin, stradayushix ginekologicheskimi zabolevaniyami– 60-98% chastota riska razvitiya raka molochnoy jelezi v 3-5 raz chashe na fone mastopatiy i v 30% sluchaev pri uzlovix formax mastopatiy snijenie zabolevaemosti mastopatiy – realniy put k snijeniyu chastoti raka molochnoy jelezi stroenie molochnix jelez molochnaya jeleza otnositsya k organam - mishenyam i sostavlyaet chast reproduktivnoy sistemi jenshini mj sostoit iz parenximi – jelezistoy tkani s proxodyashimi v ney protokami razlichnogo kalibra; stromi – soedinitelnoy tkani, razdelyayushey jelezu na doli i dolki; jirovoy tkani, v kotoruyu pogrujena parenxima i stroma jelezi strukturno-funktsionalnoy edinitsey mj yavlyaetsya alveola, vistlannaya odnim sloem jelezistix kletok - laktotsitov prl patogenez mastopatii reshayushaya rol otvoditsya narusheniyu funktsii yaichnikov (giperestrogeniya) estrogeni – vizivayut …

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slennix nablyudeniy svidetelstvuet, chto chastota viyavleniya rmj v gruppe riska bila v 22 raza vishe, chem v kontrolnoy. klinicheskie fazi mastopatii pervaya faza – vozrast 20-30 let; menstrualniy tsikl regulyarniy; za nedelyu do menstruatsii poyavlyaetsya mastodiniya; tkan jelezi uplotnena vtoraya faza - vozrast 30-40 let; mastodiniya dlitsya 2-3 nedeli do menstruatsii; v jeleze palpiruyutsya otdelnie boleznennie uplotneniya tretya faza – starshe 40 – 45 let; bol v mj menee intensivnaya i nepostoyannaya; palpiruyutsya mnojestvennie kistoznie obrazovaniya formi mastopatii diffuznaya fkm uzlovaya fkm nachalnoy stadiey obeix form mastopatii yavlyaetsya mastodiniya! diagnostika zabolevaniy molochnix jelez obuchenie jenshin samoobsledovaniyu molochnix jelez regulyarnoe klinicheskoe obsledovanie, vklyuchayushee palpatsiyu molochnix jelez luchevaya diagnostika: ejegodnoe uzi molochnix jelez jenshin do 35 let, jenshinam starshe 40 let – mammografiya 1 raz v 2 goda dopolnitelnoe issledovanie pri klinicheskix pokazaniyax samobsledovanie molochnix jelez na chto nujno obratit vnimanie pri samoobsledovanii grudi? - izmeneniya formi i razmera grudi - vtyagivanie …

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opaminergicheskogo mexanizma deystviya fibrozno-kistoznaya bolezn (mastopatiya) mastodiniya ( v tom chisle pri pms) pms besplodie, vsledstvie nedostatochnosti jt 26 mastodinon ® mastodinon ® printsip deystviya dopaminergicheskiy effekt: snijaet povishenniy uroven prolaktina prinimaet uchastie v regulyatornom tsikle gipotalamus – gipofiz – yaichniki normalizuet gormonalnoe ravnovesie rejim priema prinimat 2 raza v den po 30 kapel ili po 1 tabletke (utrom i vecherom) s nebolshim kolichestvom jidkosti minimalniy kurs - 3 mesyatsa bez pereriva vo vremya menstruatsii 27 effektivnoe ustranenie psixo - vegetativnix simptomov predmenstrualnogo sindroma patogeneticheskoe lechenie mastopatii, mastodinii ne soderjit gormonov obladaet xoroshey perenosimostyu. kak bezopasniy preparat rekomendovan v kachestve dlitelnoy terapii uluchshaet kachestvo jizni devushek i jenshin preimushestva preparata mastodinon ® pri lechenii pms i mastopatiy 28 ingibitori prostoglandinov-npvs prostaglandini : -yavlyayutsya mediatorami vospalitelnoy reaktsii: oni nakaplivayutsya v ochage vospaleniya i vizivayut lokalnoe rasshirenie sosudov, otyok, ekssudatsiyu, migratsiyu leykotsitov (v osnovnom pg-e2 i pg-i2); -sensibiliziruyut retseptori k mediatoram boli …

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bolochki, sposobstvuyushee podderjaniyu krovotoka v slizistoy; soxranenie tselostnosti granulotsitov i, takim obrazom, soxranenie strukturnoy tselostnosti slizistoy obolochki); nesomnenno, naibolee vajnim mexanizmom deystviya npvs yavlyaetsya sposobnost ingibirovat tsog - ferment, kataliziruyushiy prevrashenie svobodnix polinenasishennix jirnix kislot (araxidonovoy) v prostaglandini (pg), a takje drugie eykozanoidi - tromboksani (tra2) i prostatsiklin (pg-i2) prostaglandini farmakoterapevticheskaya gruppa: npvs. spetsificheskiy visokoselektivniy ingibitor tsog-2 retseptorov -tseloks v terapevticheskix dozax i kontsentratsiyax tseloks ne ingibiruet tsog-1. tseloks deystvuet posredstvom ingibirovaniya tsog-2 i blokiruet produktsiyu vospalitelnix prostanoidov. pokazaniya mastodiniya predmenstrualniy sindrom algomenoreya mastodiniya mastopatiya rejim dozirovki 100mg x 2 raza v sutki 200mg x 1 raz v sutki 200mg x 2 raza v sutki, v techenii 10-14 dney sistemnaya enzimoterapiya (set) - sovremenniy metod lecheniya i profilaktiki, osnovanniy na kooperativnom vozdeystvii tselenapravlenno sostavlennix smesey proteoliticheskix fermentov (enzimov) na ves organizm v tselom. osnovnie farmakologicheskie effekti set protivovospalitelniy effekt (minimizatsiya vospaleniya i uskorenie fazi reparatsii). immunomoduliruyushiy effekt (vivedenie tsirkuliruyushix kompleksov). …

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slayd 1 1 abu ali ibn sino nomidagi buxoro davlat tibbiyot instituti 2- akusherlik va ginekologiya kafedrasi «xayz oldi sindromi va mastopatiyaning oldini olish xamda davolashning zamonaviy usullari» tuzuvchilar: katta assistent: xamdamova m.t. assistent: raxmatullaeva m.m. assistent: ashurova n.g. assistent: juraev n.b. xayz kurishdan oldin yuzaga keladigan va nerv-psixik, vegeto-tomir, endokrin va somatik uzgarishlar bilan namoen buladigan simptomokompleksdir , xayz oldi sindromi xayz oldi sindromi yuzaga kelish nazariyalari: gormonal (giperestrogeniya (1931g), progesteron etishmovchiligi, gprl) «suv intoksikatsiyasi» teoriyasi allergik psixosomatik buzilishlar xozirgi vaktda xayz oldi sindromi patogenezida mns neyropeptidlari ( dofamin, noradrenalin) almashinuvining va neyroendokrin jar...

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