lektsiya №4. medlennie infektsii tsns

PPT 80 pages 2.5 MB Free download

80 pages

FaylHub.uz

Download via Telegram

Size 2.5 MB

File type PPT

Pages 80

Updated Dec 2025

Page preview (5 pages)

Scroll down 👇

1 / 80

tema :zabolevaniya nervnoy sistemi vxodyashie v gruppu medlennix infektsiy: rasseyanniy skleroz, bokovoy amiotroficheskiy skleroz i drugie. lektsiya №4. medlennie infektsii tsns. tsel lektsii: izuchit etiologiyu, patogenez, kliniku, diagnostiku i lechenie naibolee chasto vstrechayushixsya klinicheskix form medlennix infektsiy tsns – rasseyannogo skleroza, bokovogo amiotroficheskogo skleroza i dr. soglasno klassifikatsii, alpersa (1971 g.) virusnie infektsii persistentnie ostrie latentnie xronicheskie medlennie infektsii v 1835 g. kruvayler vpervie opisal klinicheskuyu kartinu rasseyannogo skleroza, kotoriy bil videlen v samostoyatelnuyu nozologicheskuyu formu sharko v 1866 g. v 1889g. on je opisal kliniku bas. v 1920-30gg. poyavilis opisaniya klinicheskoy kartini bolezni kreytsfelda-yakoba. v 1933g. davson opisal klinicheskuyu kartinu podostrogo skleroziruyushego panentsefalita, vpervie viskazal ego virusnuyu etiologiyu. v 1953g.djon-mak-artur opisal kliniku bolezni kuru. k medlennim neyrovirusnim infektsiyam otnosyatsya: 1. bolezn kuru 2. bolezn kreytsfelda-yakoba 3.podostriy skleroziruyushiy panentsefalit 4. rasseyanniy skleroz 5. bas osnovivayas na glavnix otlichitelnix priznakax etix zabolevaniy, zigurdson (1954) predlojil termin "medlennie infektsii", xarakterizuyushiesya: 1. prodoljitelnim …

2 / 80

v pishu infitsirovannogo mozga cheloveka (pri ritualnom kannibalizme). infektsiya mojet popast cherez povrejdennuyu koju, kon'yunktivu, cherez stenku kishok u detey. inkubatsionniy period ot 5 do 10 let. klinicheskaya kartina obsheinfektsionnie simptomi. progressiruyushaya piramidnaya, ekstrapiramidnaya simptomatika, ataksiya. psixomotornoe vozbujdenie, soprovojdayusheesya neuderjimim smexom, kotoriy smenyaetsya agressivnim sostoyaniem. smert nastupaet v techenie odnogo goda. lechenie simptomaticheskoe bolezn kreyttsfeldta -yakoba eto redkoe zabolevanie. otneseno k gruppe spongio-formnix entsefalopatiy, vstrechayushixsya u cheloveka i jivotnix, vizivaemix vi-rusami zamedlennogo deyst-viya. inkubatsionniy period ot 11 do 20 mesyatsev. klinika bistro progressiruyushie narusheniya: piramidnie i ekstrapiramidnie simptomi. zabolevayut litsa oboego pola v srednem vozraste. nachalnie priznaki bolezni- provali pamyati, aleksiya, golovokru-jenie, neustoychivost pri xodbe, otsutstvie initsiativi, eyforiya. vo vtoroy faze: drojanie ruk ataksiya simptomi ekstrapiramidnix i piramidnix narusheniy smeshannie giperkinezi mioklonicheskie podergivaniya rasstroystvo zreniya rechi bistro narastayushaya dementsiya. v tretey (terminalnoy) faze: narusheniya glotaniya; detserebratsiya; fleksornaya kontraktura; epilepticheskie pripadki; dementsiya; marazm. bolezn prodoljaetsya ot 10 mes. do 2 let …

3 / 80

na segodnyashniy den v mire naschitivaetsya okolo 3 mln. bolnix rasseyannim sklerozom po rasprostranyonnosti rasseyanniy skleroz zona visokogo riska zona srednego riska zona nizkogo riska v nastoyashee vremya v vozniknovenii rasseyannogo skleroza pridayut znachenie ryadu ekzogennix i endogennix faktorov. ekzogennie faktori: virusi kori respiratornie virusi adenovirusi virusi prostogo gerpesa epidemicheskiy parotit patogenez: v vozniknovenii rasseyannogo skleroza imeet znachenie sinergicheskoe deystvie ryada persistiruyushix virusnix agentov pri vedushey roli virusa kori. zabolevanie razvivaetsya u lits s geneticheski obuslovlennoy nepolnotsennostyu immunnoy sistemi na fone opredelennogo metabolizma v opredelennix geograficheskix usloviyax. xronicheskoe techenie bolezni svyazano s postoyannoy antigennoy stimulyatsiey virusnimi belkami, a takje s mexanizmami autoimmuniteta. patomorfologiya makroskopicheski v raznix otdelax golovnogo i spinnogo mozga obnarujivayutsya "skleroticheskie blyashki", imeyushie vid pyaten serovato-rozovogo tsveta razlichnoy velichini. xarakternie priznaki skleroticheskaya blyashka aktivnaya (ostraya) xronicheskaya xronicheskaya s obostreniem lokalizatsiya: spinnoy mozg mozgovoy stvol zritelnie nervi subependimarniy sloy bokovix jeludochkov zritelnie bugri kora fazi razvitiya skleroticheskoy blyashki : …

4 / 80

progressiruyushe - remittiruyushee progressiruyushee (bez remissii) medlenno progressiruyushee bistro progressiruyushee nachalo zabolevaniya bolee zreliy (30-35 let) vozrast pozdniy detskiy (13-14 let) yunosheskiy (17-19 let), klinicheskie simptomi tipichnie atipichnie rannie i tipichnie priznaki rasseyannogo skleroza: dvigatelnie rasstroystva nevrit zritelnix nervov narusheniya funktsii tazovix organov mozjechkovie rasstroystva triada sharko- nistagm, intentsionnoe drojanie, skandirovannaya rech klinicheskie simptomi triada sharko- nistagm,intentsionnoe drojanie, skandirovannaya rech pentada marburga --//-- +otsutstvie bryushnix refleksov, poblednenie visochnix polovin setchatki (oftalmoskopiya) sekstada markova --//-- +simptom piramidnogo rasshepleniya, simptom likvorologicheskogo rasshepleniya kriterii diagnostiki nachalo bolezni v molodom vozraste polimorfizm klinicheskix proyavleniy «mertsanie» simptomov daje na protyajenii sutok volnoobraznoe techenie bolezni nalichie klinicheskix dissotsiatsiy diagnosticheskiy algoritm 1. klinicheskaya kartina 2. oftalmologicheskoe obsledovanie 3. mrt golovnogo i spinnogo mozga 4. issledovanie vizvannix potentsialov golovnogo mozga 5. nalichie oligoklonalnix igg-svyazey v likvore spinno-mozgovaya jidkost izmeneniya viyavlyayut pochti u 90% bolnix. v 50% obnarujivaetsya pleotsitoz pochti u 75% bolnix povishen uroven gamma - globulinov soderjanie …

5 / 80

as) tyajeloe xronicheskoe progressiruyushee zabolevanie; xarakterizuyusheesya sistemnim porajeniem tsentralnogo i perifericheskogo dvigatelnogo neyronov; vpervie videlen sharko v 1869g. etiologiya i patogenez bas-pervichniy degenerativniy protsess, istinnaya prichina kotorogo eshyo neizvestna. imeyutsya osnovaniya predpolagat, chto zabolevanie otnositsya k gruppe medlennix infektsiy, vizivaetsya virusom. lokalizatsiya degenerativnix izmeneniy bokovie stolbi i perednie roga spinnogo mozga kora golovnogo mozga, podkorkovie obrazovaniya mozjechok stvol mozga patanatomicheskaya xarakteristika kletki umensheni, priobretayut okrugluyu ili ovalnuyu formu. pogibayushie nervnie kletki okrujeni oligodendrotsitami i makrofagami. na meste pogibshix kletok razrastayutsya glialnie elementi. znachitelnie izmeneniya obnarujivayutsya i v belom veshestve mozga. klinika spasticheskiy paralich konechnostey vyaliy paralich konechnostey mishechnie atrofii bulbarnie simptomi pervie simptomi bas registriruyutsya v vozraste 40-60 let. boleyut v osnovnom mujchini. klinicheskie formi bas sheyno-grudnaya poyasnichno-kresttsovaya bulbarnaya visokaya (tserebralnaya) klinika sheyno-grudnoy formi patologicheskie izmeneniya lokalizuyutsya: v perednix rogax; bokovix stolbax spinnogo mozga; v sheynix; verxnix grudnix segmentax. klinika sheyno-grudnoy formi nachalo zabolevaniya: 1.porajenie verxnix konechnostey v vide slabosti …

Want to read more?

Download all 80 pages for free via Telegram.

Download full file

About "lektsiya №4. medlennie infektsii tsns"

tema :zabolevaniya nervnoy sistemi vxodyashie v gruppu medlennix infektsiy: rasseyanniy skleroz, bokovoy amiotroficheskiy skleroz i drugie. lektsiya №4. medlennie infektsii tsns. tsel lektsii: izuchit etiologiyu, patogenez, kliniku, diagnostiku i lechenie naibolee chasto vstrechayushixsya klinicheskix form medlennix infektsiy tsns – rasseyannogo skleroza, bokovogo amiotroficheskogo skleroza i dr. soglasno klassifikatsii, alpersa (1971 g.) virusnie infektsii persistentnie ostrie latentnie xronicheskie medlennie infektsii v 1835 g. kruvayler vpervie opisal klinicheskuyu kartinu rasseyannogo skleroza, kotoriy bil videlen v samostoyatelnuyu nozologicheskuyu formu sharko v 1866 g. v 1889g. on je opisal kliniku bas. v 1920-30gg. poyavilis opisaniya klinicheskoy kartini bolezni kreytsfelda-yakoba...

This file contains 80 pages in PPT format (2.5 MB). To download "lektsiya №4. medlennie infektsii tsns", click the Telegram button on the left.

Tags: lektsiya №4. medlennie infektsi… PPT 80 pages Free download Telegram