tuberkulyoz

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slayd 1 tuberkulyoz epidemiologiyasi, patogenezi va immunitet fenomenlari. toshkent tibbiyot akademiyasi termiz filiali ftiziatriya fani karimov s.x. tuberkulyoz surunkali yuqumli kasallik, organizmdagi barcha a'zo va tizimlarni zararlaydi hamda og'ir asoratlarga olib keladi * tuberkulyoz global masshtabda dunyo aholisini uchdan bir qismi (2 milliard) tuberkulyoz bilan zararlangan * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of these deaths occur in the developing world. staggeringly, for a disease many of us believed would disappear in our lifetime, tb is estimated to be the commonest cause of death of young women worldwide. worse still, but at the …

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onest cause of death of young women worldwide. worse still, but at the same time providing cause for hope, these deaths are preventable. however, persistent poor practice in many countries is raising the spectre of multi-drug resistant (mdr) tb. this form of tb, if it became widely established, would make the control of the disease beyond the financial capacity of many countries. tuberkulyoz global masshtabda dunyoda har yili tuberkulyozdan 3 million odam o'ladi: ayollar – 900 000 bolalar – 300 000 * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of these deaths occur in …

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eaths occur in the developing world. staggeringly, for a disease many of us believed would disappear in our lifetime, tb is estimated to be the commonest cause of death of young women worldwide. worse still, but at the same time providing cause for hope, these deaths are preventable. however, persistent poor practice in many countries is raising the spectre of multi-drug resistant (mdr) tb. this form of tb, if it became widely established, would make the control of the disease beyond the financial capacity of many countries. insert graphic to add map map is 6.17” tall 2015 yildagi sil bilan kasallanish darajalari manba: who. (2016). global tb report 2016 tuberkulyozning tarqalishi quyidagi omillarga bog'liq: aholi sonini o'sishi - migratsiya tez urbanizatsiya aholining qashshoqligini ko'payishi oit infektsiyasini tarqalishi antibakterial preparatlarga turg'un shakllarini paydo bo'lishi. * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year …

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uberkulyozga qarshi kurashishda faol ishtirok etmasligi chorvachilikda tuberkulyoz bo'yicha epidemiologik holatning yomonligi. immunodefitsit holatlarini o'sishi antibakterial preparatlarga turg'un shakllarini paydo bo'lishi * infektsiyalanish mazkur yil davomida axoli orasida tuberkulin sinamalari o'tkazilganda sinama musbat bo'lganlarning % ko'rsatkichi kasallanish – mazkur yil davomida 100000 aholiga nisbatan birinchi marta aniqlangan tuberkulez bemorlar soni * kasalmandlik yil oxirida 100000 aholiga nisbatan faol o'pka tuberkulyozi bilan kasallangan bemorlar soni o'lim mazkur yil davomida 100000 aholiga nisbatan tuberkulyozdan o'lganlar soni rivojlangan davlatlarda 100 000 axoliga nisbatan tuberkulezdan kasallanish 10,1 10,5 6,4 6,7 8,4 9,2 9,3 10,7 15,5 18,5 17,7 20,1 15,1 17,9 7 8,5 5,7 7,3 5,2 6,8 13,8 18,4 0 5 10 15 20 25 buyuk britaniya shvetsiya niderlandi aksh finlyandiya avstriya irlandiya norvegiya italiya daniya shveytsariya konechn. nachaln o'zbekistonda silning o'lim va kasallanish intensiv ko'rsatkichlari (1996-2017 y.y.) (100 ming axoliga nisbatan) tuberkulezning patogenezi va patologik morfologiyasi tuberkulyozning yuqish yo'llari aerogen (havo-tomchi) alimentar kontakt transplatsentar …

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na stanovitsya aktivnoy i vizivaet tuberkulez tolko pri oslablenii raboti immunnoy sistemi. tuberkulyozning rivojlanishi quyidagilarga bog'liq : mbt miqdoriga kontaktning davomiyligiga mbt virulentligiga makroorganizm holatiga tuberkulyoz patogenezi mbt virulentligi mbt miqdori kontaktning davomiyligi tbning oilaviy o'chog'i tuberkulyoz mikobakteriyasi spetsifik nospetsifik (paraspetsifik) o'zgarishlar chaqiradi tuberkulyoz patogenezi mahalliy himoya: mukotsiliar klirens tizimi surfaktant tizimi fagotsitoz makrofaglarning turlari harakatlanuvchi monotsitlar gisteotsitlar fagotsitar faolligi yuqori harakatsiz taloqdagi jigardagi suyaklardagi fagotsitar faolligi kuchsiz tuberkulyoz patogenezi fagotsitoz 3 davrdan iborat: i davr makrofag retseptorlari orqali hujayra membranasiga mbtning birikishi ii davr mbt+makrofag makrofag devorlarining invaginatsiyasi(kirishi) fagosoma hosil bo'lishi fagolizosoma hosil bo'lishi iii davr fagolizasoma ishlab chiqaradigan fermentlar ta'sirida mbt lar parchalanadi va emiriladi fagotsitoz bo'linadi tugallangan tugallanmagan (tuberkulyozda ko'pincha tugallanmagan bo'ladi) tuberkulyoz patogenezi mbt m l fl i ii iii spetsifik o'zgarishning morfologik ko'rinishlari : ekssudatsiya proliferatsiya alteratsiya nekroz jarayonlaridan biri ustunlik qilishi mumkin spetsifik o'zgarishning morfologik ko'rinishlari : tuberkulyoz bo'rtmachasi granulyomalar turli o'lchamdagi o'choqlar, shikastlanish …

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slayd 1 tuberkulyoz epidemiologiyasi, patogenezi va immunitet fenomenlari. toshkent tibbiyot akademiyasi termiz filiali ftiziatriya fani karimov s.x. tuberkulyoz surunkali yuqumli kasallik, organizmdagi barcha a'zo va tizimlarni zararlaydi hamda og'ir asoratlarga olib keladi * tuberkulyoz global masshtabda dunyo aholisini uchdan bir qismi (2 milliard) tuberkulyoz bilan zararlangan * 3 the global burden of tuberculosis is truly enormous with some 1.9 million deaths per year according to the most detailed country-based analysis yet carried out and reported last year by the surveillance and monitoring unit of who's communicable disease operational and epidemiological research unit. some 380,000 of these deaths occur in hiv infected individuals largely, but not solely, in africa. and 98% of th...

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