carcinoma cervix

carcinoma cervix carcinoma cervix 509-b guruh talabasi almatova sevarabonu risk factors for carcinoma cervix early age at intercourse:<16 2 times repeated / frequent births multiple sexual partners hpv infections (type 16 & 18 highly oncogenic) low socio-economic status smoking:2-gen and immunosupresion natural history of hpv infection schiffman m, castle p. n engl j med 2005, 353:2101-2104 * site ectocervix 80% endocervix 20% gross lesion occult proliferative : friable growth ulcerative : erodes the cervix to form an irregular crater infiltrative : expands the cervix histopathology squamous cell carcinoma (80-90%) large cell keratinizing large cell non-keratinizing small cell adenocarcinoma (10-20%) endocervical clear cell adeno-squamous adeno-acanthoma spread direct vagina uterus paramet...

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